Research Paper Volume 16, Issue 11 pp 9727—9752
14-3-3σ downregulation sensitizes pancreatic cancer to carbon ions by suppressing the homologous recombination repair pathway
Figure 1. 14-3-3σ expression in PAAD and its predictive value for prognosis. (A) The expression levels of 14-3-3σ mRNA in pan-cancer. (B) The principal component analysis (PCA) analysis assessed the grouping situation of patients with different levels of 14-3-3σ expression. The K-M survival curves are plotted to predict the overall survival (OS) (C), disease-specific survival (DSS) (D), and progression-free interval (PFS) (E) of the American Type Culture Collection (TCGA) patients. The expression of 14-3-3σ in PAAD tissues in patients with different Stages (F) and Grade (G). (H) Immunohistochemistry (IHC) results of the expression levels of 14-3-3σ between PAAD and para-carcinoma tissues according to the Human Protein Atlas (HPA) database.