Research Paper Volume 16, Issue 11 pp 9692—9708
Prognostic and therapeutic roles of SETD2 in cutaneous melanoma
Figure 2. Pathways enrichment of DGEs by SETD2 expression in TCGA-SKCM and tumor tissue of SETD2 ko A375 in mouse. (A) The volcano plot exhibits the differentially expressed genes in SETD2 downregulated SKCM samples compared with its counterparts (red: upregulated genes in SETD2 downregulated SKCM samples; blue: downregulated genes in SETD2 downregulated SKCM samples). (B) The heatmap of differentially expressed genes in SETD2 downregulated SKCM samples compared with its counterparts. (C) The top enriched KEGG and GO terms by deferentially expressed genes in SETD2 downregulated SKCM samples through GSEA.