Research Paper Volume 16, Issue 10 pp 9216—9227
The protective effects of Chromofungin in oligomeric amyloid β42 (Aβ42)-induced toxicity in neurons in Alzheimer’s disease
Figure 4. Chromofungin affected the expressions of hTERT and TERF2 in oligomeric Aβ42-challenged M17 neuronal cells. Cells were stimulated with oligomeric Aβ42 (5 μM) with or without Chromofungin (0.5, 1 mM) for 24 hours. (A) mRNA expression of hTERT; (C) mRNA of p21 (n = 6, **P < 0.01 vs. vehicle group; †, ††P < 0.05, 0.01 vs. Aβ42 group).