Research Paper Volume 16, Issue 7 pp 5829—5855

Figure 2. Compound effects on oxidative stress resistance. The effect of adult exposure to (A) NP1, (B) propyl gallate, and (C) resveratrol on median survival under oxidative stress conditions, beginning at day 6 and 12 (C. elegans), or day 8 and 16 (C. briggsae) of adulthood. Three strains were tested from each species: C. elegans strains N2, MY16, and JU775 (black text), and C. briggsae AF16, ED3092, and HK104 (gray text). Each point represents the median survival on 40 mM paraquat of an individual trial plate (technical replicate), control (vehicle only – gray) or compound treated (color). The bars represent the mean +/− the standard error of the mean. Biological replicates were completed at the three CITP testing sites (square – Buck Institute, circle – Oregon, and diamond – Rutgers). Asterisks represent p-values from the CPH model such that ^****p < 0.0001, ^***p < 0.001, ^**p < 0.01, and ^*p < 0.05.