Research Paper Volume 16, Issue 7 pp 6188—6211
Potential value of expression of receptor accessory protein 4 for evaluating the prognosis of lower-grade glioma patients
Figure 1. Differential expression level of receptor accessory protein 4 (REEP4) in LGG and normal brain tissue. (A) REEP4 is significantly upregulated in 518 lower-grade glioma (LGG) and 207 normal brain tissues based on GEPIA. *p < 0·05. (B) Real-time quantitative polymerase chain reaction (RT-qPCR) of clinical samples showing elevated REEP4 expression in LGG tissues. **p < 0·01. (C) RT-qPCR showing elevated REEP4 expression in LGG cell lines. ***p < 0·001. (D, E) Immunohistochemistry shows elevated REEP4 expression in LGG tissue compared with than that in normal brain tissue. **p < 0·01.