Research Paper Volume 16, Issue 7 pp 6147—6162
Poria cocos polysaccharides improve alcoholic liver disease by interfering with ferroptosis through NRF2 regulation
Figure 5. Effects of Poria cocos polysaccharides (PCPs) on the mRNA expression of Nrf2, ferroptosis, and other indicators in the liver tissue of alcoholic liver disease (ALD) rats. (A) NF-κβ. (B) A comparison of MyD88 results. (C) A comparison of HO-1 results. (D) A comparison of Nrf2 results. (E) A comparison of FTH1 results. (F) A comparison of interleukin (IL)-1β results. (G) A comparison of IL-6 results. (H) A comparison of GPX4 results. (I) A comparison of the results of glutathione. The reported values are presented as mean ± SD, n = 8. *P< 0.05, ***P<0.01, compared with the control group; #P<0.05, ###P<0.01, compared with the ALD group; x P<0.05, xxx P<0.01, compared with the ML385 group.