Research Paper Volume 16, Issue 7 pp 6135—6146

Lifibrate attenuates blood-brain barrier damage following ischemic stroke via the MLCK/p-MLC/ZO-1 axis

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Figure 2. Lifibrate ameliorated aggravation in blood-brain barrier (BBB) permeability in a middle cerebral artery occlusion (MCAO) mice model. Blood-brain barrier permeability was assayed by Evans blue staining (n=10, **, P<0.01 vs. vehicle group; ^^, P<0.01 vs. MCAO group).