Research Paper Volume 16, Issue 7 pp 6135—6146
Lifibrate attenuates blood-brain barrier damage following ischemic stroke via the MLCK/p-MLC/ZO-1 axis
Figure 1. Lifibrate decreased brain infarction volume and improved neurological dysfunction in a middle cerebral artery occlusion (MCAO) mice model. Mice were divided into 3 groups: (1) Vehicle; (2) MCAO; (3) Lifibrate+MCAO. (A) Quantification of infarction volume; (B) Neurological score graph of the three experimental groups (n=10, **, P<0.01 vs. vehicle group; ^^, P<0.01 vs. MCAO group).