Figure 12. Immunohistochemical validation of immune cell infiltration. Identifying the differences in immune cell biomarkers and their presence in periorbital adipose tissue of thyroid ophthalmopathy patients and normal controls (x200). (A) CD4; (B) CD8; (C) CD19; (D) CD 20; (E) Foxp3; (F) CD25; (G) PC1. *P < 0.05, **P < 0.01, ***P < 0.001.