Research Paper Volume 16, Issue 7 pp 5987—6007

Figure 5. Fer-1 reduces CaOx crystal deposition and kidney injury in CaOx nephrolithiasis rat models. (A) Pathological sections including HE, VK, and Masson staining show the degree of kidney injury, crystal deposition, and kidney fibrosis; PB staining shows the Fe³⁺, while IHC staining shows GPX4 protein expression in different groups (magnification×20; scale bar, 200 μm). (B) SOD, MDA, GSH, and Fe²⁺ levels are detected in different groups (mean ± SD, n = 6, *P < 0.05, **P < 0.01).