Research Paper Volume 16, Issue 7 pp 5929—5948
RNA splicing regulator EIF3D regulates the tumor microenvironment through immunogene-related alternative splicing in head and neck squamous cell carcinoma
Figure 1. Expression level and prognosis of EIF3D in HNSC. (A) Box plot illustrating the expression level of EIF3D in pan-cancer dataset. (B, C) Box plots displaying EIF3D expression levels in a cohort of 566 HNSC samples retrieved from the TCGA database, encompassing 522 tumor samples and 44 normal samples. Error bars indicate the mean ± SEM. Significance denoted by P < 0.05. (D, E) Survival curves depicting the impact of EIF3D expression on HNSC patient survival, as determined from the TCGA databases. (F, G) Univariate and multivariate Cox regression analyses. Significance levels: *P-value < 0.05, **P-value < 0.01, ***P-value < 0.001.