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Research Paper|Volume 16, Issue 7|pp. 5916–5928
Downregulating miRNA-199a-5p exacerbates fluorouracil-induced cardiotoxicity by activating the ATF6 signaling pathway
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Figure 7
Figure 7.5-FU causes the decreased expression of miRNA-199a-5p and activated the ATF6 and PERK in endoplasmic reticulum stress, which led to the up regulation of CHOP expression.