Geraniol attenuates oxidative stress and neuroinflammation-mediated cognitive impairment in D galactose-induced mouse aging model

Peramaiyan Rajendran; Fatma J. Al-Saeedi; Rebai Ben Ammar; Basem M. Abdallah; Enas M. Ali; Najla Khaled Al Abdulsalam; Sujatha Tejavat; Duaa Althumairy; Vishnu Priya Veeraraghavan; Sarah Abdulaziz Alamer; Gamal M. Bekhet; Emad A. Ahmed

doi:doi:10.18632/aging.205677

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Research Paper Volume 16, Issue 6 pp 5000—5026

Geraniol attenuates oxidative stress and neuroinflammation-mediated cognitive impairment in D galactose-induced mouse aging model

Figure 3. Effect of GNL on antioxidant activity in D-gal-induced mice serum and hippocampus. (A) serum, MDA level control, and treated animals (nmol/mg protein), (B) SOD (U/mg protein), (C) CAT (U/mg protein), and (D) GPx (U/mg protein). (E) Hippocampus MDA level control and treated animals (nmol/mg protein), (F) SOD (U/mg protein), (G) CAT (U/mg protein), and (H) GPx (U/mg protein). Values are expressed as the mean ± SD (n = 6). ^*P < 0.05 vs. control group, ^#P < 0.05 vs. D-gal alone-treated mice. ^@P < 0.05 young vs. old mice.