Research Paper Volume 16, Issue 6 pp 4980—4999
CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction
Figure 4. Adipose tissue metabolic markers were evaluated in mice fed with CMS121 for 6 months. Representative slot blot (A) or Western blot (B) images of mitochondrial fractions from adipose tissue are presented. Quantitative results (C–K) of proteins related to mitochondrial metabolism, such as transcription factors Nrf1 (C) and TFAM (D), markers of lipid (p-ACC1, (E)) and glucose (GLUT4, (F)) metabolism, and markers of mitochondrial complex I ((G); NDUFB8), complex II ((H); SDHB), complex III ((I); UQCRC2), and complex V ((J); ATP5A) are presented, as well as the levels of the outer membrane translocase TOM20 (K). Data are presented as mean + SD (n = 6–8). Bold underlined values of p indicate statistical differences.