Research Paper Volume 16, Issue 6 pp 5703—5710
M1 intestinal macrophages-derived exosomes promote colitis progression and mucosal barrier injury
Figure 5. Suppressing TLR4 signal antagonizes the effect of M1-Exo on tissue pathology. (A) H&E (n = 5). Res improved mouse intestinal inflammation and epithelial cell injury, and decreased the inflammatory response in intestinal tissue. (B, C) Relative protein levels (n = 5). Res reduced TLR4 expression. *P < 0.05 versus Control group, #P < 0.05 versus DSS group.