Figure 5. The expression of CRIF1 was decreased in DOX-induced AC16 cells. (A) The cell activity was detected by CCK8. (B) RT-qPCR detected the expression of p27, p21, and p16 in AC16 cells. (C) The protein expression of CRIF1 was examined by western blot. *P<0.05, **P<0.01, ***P<0.001 vs Control.