Research Paper Volume 16, Issue 6 pp 5435—5451
Identification of key lncRNAs in age-related macular degeneration through integrated bioinformatics and experimental validation
Figure 9. Cell migration analysis. (A) Control group. (B) t-BH group. (C, D) RPE-19 cells after t-BH treatment. (C) is the negative control. (D) is transfected with LINC00276 overexpression vector, cell migration rate was significantly reduced in the senescent cell model. (E) Migration rate of cells was determined using Transwell assays. (F, G) mRNA levels of IFIT3 and LINC00276 were detected by RT-PCR. The expression of LINC00276 was significantly improved after plasmid construction and stable transduction. After LINC00276 was upregulated, the migration rate was improved. *** means P<0.001, ** means P<0.01 compared with control group, ### means P<0.001 compared with t-BH group. NC means negative control.