Figure 5. Identification of key genes for IVDD. (A) Cluster dendrogram of 39 IVD. (B) The scale independent value exceeded 0.9 with a low average connectivity when the soft threshold power was 5. (C) Cluster dendrogram of disease genes to identify clinically meaningful modules associated with IVDD development. (D) Heatmap of the correlation between gene modules and clinical traits of IVDD. (E) The scatterplot of Gene Significance vs. Module Membership in the turquoise modules.