Research Paper Volume 16, Issue 6 pp 5370—5386

Comprehensive analysis of gene expression profiles of annulus fibrosus subtypes and hub genes in intervertebral disc degeneration

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Figure 4. Identification of key genes for clustering. (A) Cluster dendrogram of 21 IVDD. (B) The scale independent value exceeded 0.9 with a low average connectivity when the soft threshold power was 6. (C) Cluster dendrogram of clustered genes to identify clinically meaningful modules associated with cluster occurrence. (D) Heatmap of the correlation between gene modules and clinical traits of IVDD. (E) The scatterplot of Gene Significance vs. Module Membership in the turquoise modules.