Figure 9 — Antagomir of miR-31-5p modulates macrophage polarization via the AMPK/SIRT1/NLRP3 signaling pathway to protect against DSS-induced colitis in mice

Research Paper|Volume 16, Issue 6|pp. 5336–5353

Antagomir of miR-31-5p modulates macrophage polarization via the AMPK/SIRT1/NLRP3 signaling pathway to protect against DSS-induced colitis in mice

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Figure 9.Antagomir of miR-31-5p can activate AMPK/SIRT1-dependent signaling to inhibit NLRP3 inflammasome in macrophages and promote the transformation of M1-type macrophages to M2-type macrophages to improve inflammatory response in colitis.