Research Paper Volume 16, Issue 6 pp 5336—5353
Antagomir of miR-31-5p modulates macrophage polarization via the AMPK/SIRT1/NLRP3 signaling pathway to protect against DSS-induced colitis in mice
Figure 1. The highly expressed miRNA molecules that can target AMPK in UC were systematically screened. (A) Heat map and volcano map of DEmiRNAs. (B) Intersection diagram and cytoscape diagram of DEmiRNAs and AMPK-targeting miRNAs. (C) Path compression diagram and model diagram of LASSO regression. (D) Diagnostic model of mmu-miR-449C-5p and mmu-miR-31-5p (nomogram). (E) ROC curve and DCA curve of model validation.