Research Paper Volume 16, Issue 6 pp 5264—5287

Figure 9. Correlations between COPS subunit gene expression levels and immune cell infiltration rates. (A) Correlations of COPS subunit expression levels with infiltration rates of B cells, CD8+ T cells, CD4+ T cells, macrophages, neutrophils, and dendritic cells in HCC (from the TIMER2.0 database). (B) Relationships among the infiltration levels of 24 immune cell types and COPS subunit expression profiles (based on the ssGSEA R package). (C) Relationships between COPS subunit expression levels and stromal score, immune score, and ESTIMATE score. (D) Heatmaps showing the correlations between COPS subunit expression levels and immunostimulators, immunoinhibitors, MHC molecules, chemokines, and chemokine receptors in HCC (TISIDB).