Figure 6. 5-HTP significantly improves doxorubicin-induced mitochondrial dysfunction in mice hearts. (A) Scatter plot of KEGG enrichment analysis of upregulated genes by H-5-HTP group; (B) Changes in oxygen consumption in mouse heart tissue in the different intervention groups; (C) Respiration rate of mouse heart tissue in state 4, state 3 and after addition of oligomycin in different treatment groups; (D) Changes in control rate of mouse heart respiration. *P < 0.05 vs. the Control group, #P < 0.05 vs. the DOX group. (H-5-HTP group: H-5-HTP+DOX).