Research Paper Volume 16, Issue 5 pp 4889—4903
5-Hydroxytryptophan acts as a gap junction inhibitor to limit the spread of chemotherapy-induced cardiomyocyte injury and mitochondrial dysfunction
Figure 3. 5-HTP ameliorates DOX-induced morphological damage of myocardial tissue in mice. (A) Scans of heart tissue sections; (B) The results from HE staining, bar = 100 μm; (C, D) The results and extent of fibrosis from MASSON staining, bar = 50 μm; *P < 0.05 vs. the Control group, #P < 0.05 vs. the DOX group. (L-5-HTP group: L-5-HTP+DOX; M-5-HTP group: M-5-HTP+DOX; H-5-HTP group: H-5-HTP+DOX).