Research Paper Volume 16, Issue 5 pp 4862—4888
Molecular characteristics and prognostic significances of lysosomal-dependent cell death in kidney renal clear cell carcinoma
Figure 7. LASSO-Cox analysis was used for identifying the hub LDCD-RGs. (A) LASSO plot of LDCD-RGs mRNA in KIRC. (B) Cross-validation of the constructed model. (C) Multivariable Cox regression analysis of LDCD-RGs. Identified 14 target genes for model construction, including: MAP1LC3C, AHR, BAG3, HGS, CLOCK, LAMTOR5, GABARAPL2, MCOLN3, UBB, VPS33A, SMCR8, PHLPP1, SIGLEC15, and C1orf220. Abbreviations: LASSO: Least absolute shrinkage and selection operator; LDCD-RGs: LDCD-related genes; KIRC: kidney renal clear cell carcinoma.