Research Paper Volume 16, Issue 5 pp 4789—4810
SORBS1 inhibits epithelial to mesenchymal transition (EMT) of breast cancer cells by regulating PI3K/AKT signaling and macrophage phenotypic polarization
Figure 6. SORBS1 inhibits the PI3K/AKT signaling pathway. (A) The expression of PI3K, p-PI3K, AKT, and p-AKT proteins was detected by Western blot assay in MDA-MB-231 cells. (B) Expression of PI3K, p-PI3K, AKT, p-AKT proteins was detected by Western blot assay in SKBR3 cells. (* P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001).