Figure 6 — SORBS1 inhibits epithelial to mesenchymal transition (EMT) of breast cancer cells by regulating PI3K/AKT signaling and macrophage phenotypic polarization

Research Paper|Volume 16, Issue 5|pp. 4789–4810

SORBS1 inhibits epithelial to mesenchymal transition (EMT) of breast cancer cells by regulating PI3K/AKT signaling and macrophage phenotypic polarization

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Figure 6.SORBS1 inhibits the PI3K/AKT signaling pathway. (A) The expression of PI3K, p-PI3K, AKT, and p-AKT proteins was detected by Western blot assay in MDA-MB-231 cells. (B) Expression of PI3K, p-PI3K, AKT, p-AKT proteins was detected by Western blot assay in SKBR3 cells. (^*P < 0.05, ^**P < 0.01, ^***P < 0.001, ^****P < 0.0001).