Figure 5 — SORBS1 inhibits epithelial to mesenchymal transition (EMT) of breast cancer cells by regulating PI3K/AKT signaling and macrophage phenotypic polarization

Research Paper|Volume 16, Issue 5|pp. 4789–4810

SORBS1 inhibits epithelial to mesenchymal transition (EMT) of breast cancer cells by regulating PI3K/AKT signaling and macrophage phenotypic polarization

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Figure 5.SORBS1 can regulate EMT-related proteins. (A) The expression of EMT-related proteins was detected 48 h after transfection of MDA-MB-231 cells with siRNA and overexpression plasmid of SORBS1. (B) The expression of EMT-related proteins was detected after transfecting SKBR3 cells with siRNA and overexpression plasmid of SORBS1 for 48 h. (^*P < 0.05, ^**P < 0.01, ^***P < 0.001, ^****P < 0.0001).