Research Paper Volume 16, Issue 5 pp 4789—4810
SORBS1 inhibits epithelial to mesenchymal transition (EMT) of breast cancer cells by regulating PI3K/AKT signaling and macrophage phenotypic polarization
Figure 5. SORBS1 can regulate EMT-related proteins. (A) The expression of EMT-related proteins was detected 48 h after transfection of MDA-MB-231 cells with siRNA and overexpression plasmid of SORBS1. (B) The expression of EMT-related proteins was detected after transfecting SKBR3 cells with siRNA and overexpression plasmid of SORBS1 for 48 h. (* P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001).