Research Paper Volume 16, Issue 5 pp 4723—4735
A Mendelian randomization analysis identifies causal association between sarcopenia and gastroesophageal reflux disease
Figure 2. Causal effects of sarcopenia traits on gastroesophageal reflux disease. (A) Forest plot for causal effects of sarcopenia traits on gastroesophageal reflux disease. (B) Scatter plot for causal effects of low hand grip strength, usual walking pace, and appendicular lean mass on gastroesophageal reflux disease, respectively. Analyses were performed by using the Inverse variance weighted, MR Egger, Weighted median, Weighted mode, and Maximum likelihood methods. The slope of each line corresponds to the estimated MR effect per method. GERD, gastroesophageal reflux disease; ALM, appendicular lean mass; MR, Mendelian randomization; SNP, single nucleotide polymorphism.