Figure 6. Histology and immunohistology of skin tissue and spleen sections. (A) H&E staining of paraffin sections of the dorsal skin and comparison of epidermal layer thickness. Scale bar: 200 μm. (B) Spleen sections and circumferential comparisons of mice from each group. Scale bar: 2 mm. (C, D) CCNE1 and CDC6 antibody staining of skin tissue sections for immunohistology analysis. Scale bar: 100 μm. The data are presented as the mean ± SD (n = 5). *p < 0.05; **p < 0.01.