Research Paper Volume 16, Issue 6 pp 5108—5122
Portulaca oleracea L. polysaccharide inhibits ovarian cancer via inducing ACSL4-dependent ferroptosis
Figure 2. POL inhibits migration and induces cell death in ovarian cancer cells. Scratch assay revealed that 50 and 100 μg/ml of POL significantly inhibited the migration of SKOV3 (A) and Hey (B) cells at 48 h (4×). Transwell assay revealed that POL effectively inhibited the migration of SKOV3 (C) and Hey (D) cells (20×). Flow cytometry results assay revealed that 50 and 100 μg/ml of POL significantly increased the mortality of SKOV3 (E) and Hey (F) cells. *P < 0.05, **P < 0.01, ***P < 0.001 vs. Con.