Research Paper Volume 16, Issue 6 pp 5091—5107
GSG2 promotes thyroid cancer via stabilizing AURKB and activating AKT pathway
Figure 5. The exploration of downstream pathway of GSG2-regulating thyroid cancer. (A, B) After treating GSG2-depleted B-CPAP and TPC-1 cells with AKT activator, cell proliferation (A) and apoptosis (B) were assessed via CCK8 assay and flow cytometry experiments. (C) Total protein and phosphorylation levels of AKT were determined in GSG2-depleted B-CPAP and TPC-1 cells following AKT activator addition. Results were presented as mean ± SD. * P < 0.05, ** P < 0.01, ***P < 0.001.