Research Paper Volume 16, Issue 5 pp 4378—4395
The prognosis, chemotherapy and immunotherapy efficacy of the SUMOylation pathway signature and the role of UBA2 in lung adenocarcinoma
Figure 2. Construction of a SUMOPS to predict the prognosis of LUAD patients. (A) LASSO coefficient profile illustrating the relationship between overall survival and partial likelihood deviation. (B) Distribution of LASSO coefficients for the SUMOPS genes, indicating their respective contributions to the model. (C) Distribution of SUMOPS expression, survival status, and SUMOPS gene expression in the TCGA-LUAD dataset. (D) Prognostic analysis investigating the role of SUMOPS in predicting outcomes in the TCGA-LUAD cohort. (E) ssGSEA analysis of SUMOPS-low and SUMOPS-high subtypes. (F) Correlation analysis using Spearman’s rank correlation to examine the associations between SUMOPS and known gene signatures. −p > 0.05; **p < 0.01, ***p < 0.001.