Figure 6 — Probucol protects against brain damage caused by intra-neural pyroptosis in rats with vascular dementia through inhibition of the Syk/Ros pathway

Research Paper|Volume 16, Issue 5|pp. 4363–4377

Probucol protects against brain damage caused by intra-neural pyroptosis in rats with vascular dementia through inhibition of the Syk/Ros pathway

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Figure 6.Probucol reduces oxidative stress and pyroptosis in microglial cells treated with LO/LG. (A) WB assay of p-Syk and oxidative stress markers (gp91^phox, p47^phox, and p22^phox). (B) Statistical data of WB assay results. (C) WB assay of pyroptosis markers (NLRP3, ASC, and Caspase-1). (D) Statistical data of WB assay results. Data are expressed as mean ± SEM. n = 3/group. ^**P < 0.01: LO/LG group vs. Probucol group.