Research Paper Volume 16, Issue 5 pp 4327—4347
4-Hydroxyphenylpyruvate Dioxygenase-Like predicts the prognosis and the immunotherapy response of cancers: a pan-cancer analysis
Figure 8. HPDL promote tumor growth, migration, and cell cycle in LUAD cells. (A) The level of HPDL transfection with siRNA were analyzed by WB. (B) The expression of Cyclin B1, Cyclin E1, and HPDL was analyzed by WB. (C) Colony formation assays showed that knockdown of HPDL inhibited LUAD cell growth. (D) Transwell assay showed that HPDL silencing inhibited the migrating of A549 and PC9 cells. (E) CCK8 assay was performed to determine the proliferation of HPDL knockdown. The labelled asterisk indicated the statistical p-value (*p < 0.05, **p < 0.01, ***p < 0.001).