Research Paper Volume 16, Issue 6 pp 5050—5064

Figure 4. Omilancor alleviated senescence mediated IDD in vivo. (A, B) X-ray images and disc height analysis of rats from the CTR, AFP plus PBS, and AFP plus OMLC groups, taken 8 weeks post-operation. (C, D) MRI images and Pfirrmann grade analysis of rats from the CTR, AFP plus PBS, and AFP plus OMLC groups, obtained 8 weeks after surgery. (E, F) H&E and IF staining depicting MAP2K6 and P21 in rats from the CTR, AFP plus PBS, and AFP plus OMLC groups, conducted 8 weeks post-operation. (Original magnification 200×, scale bar = 200 μm). CTR, control group; AFP, annulus fibrosus puncture group; n = 3 each group. Data are represented as mean ± standard deviation. ns: not significant, *p < 0.05, **p < 0.01, ***p < 0.001, as determined by one-way ANOVA with post-hoc Bonferroni correction or Kruskal-Wallis H test with a Dunn’s correction.