Figure 2. Construction of WGCNA co–expression network in validation set. (A) Scale-free fit index and mean connectivity analysis for various soft-thresholding powers. (B) Clustered dendrograms were cut at 0.25 heights to recognize and connect related modules. (C) Cluster dendrograms and module assignment for WGCNA modules. The colored horizontal bar represents the modules. (D) Collinear heat map of module feature genes. The color red represents a high correlation, whereas the color blue suggests the opposite results. (E) Visualization of the WGCNA network heatmap. The heatmap shows the topological overlap matrix (TOM) for each module. (F) Module-trait correlations. Positive correlations are represented by red and negative correlations by blue.