Research Paper Volume 16, Issue 4 pp 3612—3630
New insights into ginsenoside Rg1 regulating the niche to inhibit age-induced germline stem cells depletion through targeting ECR/BMP signaling pathway in Drosophila
Figure 6. Effect of ginsenoside Rg1 on niche ECR/BMP signaling in Drosophila. (A) Western blotting analysis of expression of ISWI, Decapentaplegic (Dpp) and Smad4; (B) Relative expression levels of ISWI; (C) Relative expression levels of Dpp; (D) Relative expression levels of Smad4; (E) Western blotting analysis of expression of pSmad1/5/8; (F) Relative pSmad1/5/8 expression levels; GAPDH antibody was used as loading Control. Results were analysed with one-way ANOVA. Data are shown as the mean ± SD (n = 100); ###p < 0.001 compared with Control (7-day-old female Drosophila); ***p < 0.001 compared with Model (35-day-old female Drosophila); +++p < 0.001 compared with Control (7-day-old female Drosophila); Abbreviation: ns: no significance.