Research Paper Volume 16, Issue 4 pp 3612—3630
New insights into ginsenoside Rg1 regulating the niche to inhibit age-induced germline stem cells depletion through targeting ECR/BMP signaling pathway in Drosophila
Figure 4. Effect of ginsenoside Rg1 on ECR. (A) The chemical structure of ecdysterone; (B) The chemical structure of ginsenoside Rg1; (C) Relative mRNA-level expression of gene encoding ECR; (D) 3D diagrams of the docked structure of ecdysterone in the active domain of the ECR; (E) 2D diagrams of the docked structure of ecdysterone in the active domain of the ECR; (F) 3D diagrams of the docked structure of ginsenoside Rg1 in the active domain of the ECR; (G) 2D diagrams of the docked structure of ginsenoside Rg1 in the active domain of the ECR. Results were analysed with one-way ANOVA. Data are shown as the mean ± SD (n = 100); ###p < 0.001 compared with Control (7-day-old female Drosophila); **p < 0.01, ***p < 0.001 compared with Model (35-day-old female Drosophila).