Research Paper Volume 16, Issue 4 pp 3583—3595

Rutin promotes osteogenic differentiation of mesenchymal stem cells (MSCs) by increasing ECM deposition and inhibiting p53 expression

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Figure 2. Transcriptome analysis of rutin effects on osteogenic differentiation of MSCs. (A) Principal component analysis (PCA) plot of the transcriptome data. (B) Heatmap of relative expression of genes across samples. (C) The volcano plot shows the differentially expressed genes (DEGs).