Research Paper Volume 16, Issue 4 pp 3554—3582

Figure 8. Detection of tumorigenesis of SLC30A7 stably knocked down in nude mouse orthotopic implanted tumour model. (A) Representative images of bioluminescence of mice on days 7, 14, and 28 after implantation. (B) Quantitative analysis of these bioluminescence images for the Scramble, shSLC30A7-1 and shSLC30A7-2 treatment groups. Data are shown as the mean ± S.D. n = 6, ^****P < 0.0001 compared to the control, Student’s t-test. (C) The overall survival of mice in different groups. Data are shown as the mean ± S.D. n = 6, ^NSP > 0.05, ^**P < 0.01 compared to the control, ANOVA test. (D) Representative images of the HE (×4 magnification, scale bar = 1000 μm) and HE staining in local area enlargement of tumour (×40 magnification, scale bar = 200 μm). The three rows of HE samples are repeated data from different processing groups. The outlined sections of left images were defined as higher magnification sections right.