Research Paper Volume 16, Issue 4 pp 3363—3385
Pan-cancer analysis of NUDT21 and its effect on the proliferation of human head and neck squamous cell carcinoma
Figure 5. NUDT21 is involved in chromatin remodeling, cancer immunity, and related pathways. (A) PPI protein interactions network of NUDT21. (B) Box plots of NUDT21 expression between somatic alteration groups or non-alteration groups at the level of 11 cancer pathways were obtained by the UALCAN web tool. (C) Correlation between NUDT21 and the top 5 co-expressed genes in each cancer type (left) and in all cancer samples (right). Spearman_Cor indicates biased correlation. (D) STRING plots of the top 100 NUDT21 co-expressed genes identified on GEPIA2.0 enriched for GO pathways. Only the top genes of each pathway are listed at the left end of the corresponding ribbon. (E) Enrichment maps of KEGG and HALLMARK in pan-cancer were analyzed by GSEA, divided by median expression of NUDT21.