Research Paper Volume 16, Issue 4 pp 3363—3385

Figure 2. Differential expression of NUDT21 and predicted survival in pan-cancer. (A) Analysis of NUDT21 associated diseases using the Open Target web tool. The red dashed line indicates NUDT2 associated cancers. (B) Gene expression levels of NUDT21 in pan-cancerous tissues and its corresponding control tissues were analyzed using the TIMER2.0 method. Tumor and normal tissues are indicated in red and blue and SKCM metastatic tissues in purple, respectively. (C) Box plots of gene expression levels of NUDT21 in tumor and normal tissues of seven cancer types were plotted on GEPIA2.0. T and N represent tumor and normal tissues. (D) The expression levels of NUDT21 in four tumor types at four different stages were analyzed using the GEPIA2.0 method. (E) The UALCAN method was used to compare the protein expression differences of eight tumor tissues between normal and tumors tissues. (F) Kaplan-Meier curves were plotted to predict OS (red), DSS (blue) and PFI (green) in TCGA patients, * represents p<0.05, ** represents p<0.01, *** represents p<0.001.