Research Paper Volume 16, Issue 6 pp 5027—5037
Phoenixin 20 ameliorates pulmonary arterial hypertension via inhibiting inflammation and oxidative stress
Figure 3. PHN-20 mitigated inflammatory response and oxidative stress in lung tissues of pulmonary arterial hypertension (PAH) rats. (A) mRNA levels of TNF-α, IL-6, and MCP-1; (B) Protein of TNF-α (pg/ml), IL-6 (pg/ml), and MCP-1 (pg/ml) was measured by ELISA; (C) The levels of MDA (nmol/mg protein) in lung tissues were measured using a commercial kit; (D) The SOD activity (U/mg protein) in lung tissues was measured using a commercial kit. (**, P<0.01 vs. control group; ##, P<0.01 vs. hypoxia group).