Research Paper Volume 16, Issue 2 pp 1298—1317

Figure 3. α-Hederin decreases A549/DPP cell growth in vivo. (A) Representative images of xenograft tumors isolated from nude mice in the different groups. (B) Tumor sizes in the different groups. (C) Representative images of Tunel, Ki-67, CD44, E-Cad staining isolated from nude mice xenograft tumor tissues in the different groups. (D) Live imaging showing metastasis of A549/DPP cells of an intravenous tail injection with α-Hederin in different weeks. (E) Representative images of orthotopic tumor model isolated from nude mice in the different groups and HE, Tunel, Ki-67, CD44, E-Cad staining in orthotopic lung tissue. (n = 5). Data are shown as mean ± SD, One-way ANOVA, ^*P < 0.05, ^**P < 0.01, ^***P < 0.001.