Research Paper Volume 16, Issue 2 pp 1298—1317
α-Hederin promotes ferroptosis and reverses cisplatin chemoresistance in non-small cell lung cancer
Figure 2. α-Hederin decreases metastasis and stemness in cisplatin-resistant NSCLC cells. (A, B) Cell migration and invasion were detected by Transwell assay. (C) Western blot demonstrating E-cadherin, N-cadherin, and Snail levels in NSCLC cells after treatment with α-Hederin for 24 hours. (D) The spheroid formation ability assessed in NSCLC cells. (E) Western blot demonstrating CD44 and CD133 levels in NSCLC cells. (n = 3). Data are shown as mean ± SD, One-way ANOVA.