Research Paper Volume 16, Issue 2 pp 1298—1317

Figure 1. α-Hederin reduces cisplatin resistance in cisplatin-resistant NSCLC cell lines. (A) CCK8 results showing the viability of cisplatin-resistant A549/DPP and PC-9/DPP cell lines after treatment with different concentrations of α-Hederin for 24 hours. (B) CCK8 results showing the viability of A549/DPP and PC-9/DPP cell lines after treatment with different concentrations of α-Hederin for 0, 24, 48, and 72 hours. (C) CCK8 results showing the viability of cell after treatment with different concentrations of cisplatin for 24 hours. (D) Colony formation assay showing proliferation in NSCLC cells after treatment with α-Hederin for 24 hours. (E) Cell apoptosis detected by flow cytometry. (F) Propidium iodide (PI) staining (red) indicates apoptotic/necrotic cells. (n = 3). Data are shown as mean ± SD, One-way ANOVA, ^***P < 0.001.