Research Paper Volume 16, Issue 1 pp 593—616

Integrated multi-omics analyses reveal the TM4SF family genes with prognostic and therapeutic relevance in hepatocellular carcinoma

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Figure 6. Construction of the TM4SFs-based risk score for prognostic evaluation. (A) The survival time of LIHC patients with different risk scores. (B) The survival curve for the TM4SFs-based risk score of the LIHC cohort in TCGA. (C) Multivariable Cox regression analysis demonstrated that the risk models were independent predictors of prognosis for LIHC patients. (D) A nomogram was constructed using the multivariable analysis results (age, sex, stage, and risk score) to visualize the model. (E) The calibration plots for the 3- and 5-year OS were predicted well in the TCGA cohort. (F) Time-dependent ROC curves of the risk score for predicting 3- and 5-year survival rates in the pooled HCC cohort.