Research Paper Volume 16, Issue 1 pp 593—616
Integrated multi-omics analyses reveal the TM4SF family genes with prognostic and therapeutic relevance in hepatocellular carcinoma
Figure 12. TM4SF4 silencing suppressed the migration and invasion of LIHC cells. (A) Scratch healing experiments were used to detect the migration ability of TM4SF4 silencing cells. (B) Transwell assays of cell invasion were performed to test the effects of TM4SF4 knockdown invasion of HepG2 and HuH7 cells. (C) Cell migration was assayed using a high-content imaging system and analyzed by the mean square displacement and speed. *p < 0.05, **p < 0.01, ***p < 0.001.