Research Paper Volume 16, Issue 1 pp 568—592
Immune landscape and heterogeneity of cervical squamous cell carcinoma and adenocarcinoma
Figure 3. Identification of differentially expressed IRGs between CSCC and ADC. (A) Identification of 54 differentially expressed IRGs affecting patients’ prognosis between CSCC and ADC. IRGs refers to the gene list of immune related genes from the online ImmPort database. DEGs refers to the differentially expressed genes between CSCC and ADC. Prognostic genes refer to the genes affecting patients’ prognosis in cervical cancer. (B) Heatmap of 54 differentially expressed IRGs in CSCC and ADC cohorts. (C) PCA analysis of 54 differentially expressed IRGs in cervical cancer. (D) Receiver operating characteristic (ROC) curve based on 54 differentially expressed IRGs in cervical cancer. (E) Functional enrichment analysis of these 54 differentially expressed IRGs. (F) Relationships between different immunocytes infiltration abundance and 54 IRGs expression level. IRGs: immune related genes; PCA: principal component analysis. * P <0.05.