Research Paper Volume 16, Issue 1 pp 445—465

Tumor-associated macrophages and PD-L1 in prostate cancer: a possible key to unlocking immunotherapy efficacy

class="figure-viewer-img"

Figure 5. M2 macrophage infiltration is a key factor involved in immune modulation in PCa. (A, B) Gene set enrichment analysis (GSEA) of PCa patients with high and low infiltration levels of M2 macrophages in the TCGA-PRAD dataset. (C, D) GSEA analysis of PCa patients with high and low infiltration levels of M2-TAMs in prad_su2c_2019 dataset. (EH) Kaplan-Meier analysis of PCa patients with high or low infiltration levels of T regulatory cells, T memory cells, B memory cells, and B plasma cells with PFS in TCGA-PRAD dataset.